Thiago Silva and N’Golo Kante will be injury doubts as defender Silva hobbled out of the 3-1 Boxing Day win at Aston Villa with a thigh issue, though Chelsea hope to have caught the problem before a major flare-up.
Kante will be checked for a knee issue, while Timo Werner and Kai Havertz could return after Covid isolation but Ruben Loftus-Cheek is a doubt with a foot injury.
Ben Chilwell's knee problem looks more serious and the England man could miss the remainder of the campaign.
Scroll down and click through to see how Chelsea could line up for this one.